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Chicken Bubble Biscuit Bake Casserole

A comforting casserole packed with tender chicken, creamy sauce, and fluffy biscuits, perfect for any weeknight dinner.
Prep Time 15 minutes
Cook Time 35 minutes
Total Time 50 minutes
Course Dinner, Main Course
Cuisine American
Servings 6 servings
Calories 350 kcal

Ingredients
  

For the filling

  • 2 cups cooked chicken (shredded or diced; rotisserie works great)
  • 1 can cream of chicken soup (or cream of mushroom) 10.5 oz size
  • 1/2 cup sour cream (or plain Greek yogurt)
  • 1/2 cup milk
  • 1 cup frozen mixed vegetables (peas, carrots, corn, beans)
  • 1 tsp garlic powder
  • 1/2 tsp onion powder
  • to taste Salt & pepper

For the topping

  • 1 can refrigerated biscuit dough 16 oz, cut into quarters
  • 1 cup shredded cheddar cheese (or mozzarella)
  • 1 tbsp melted butter optional, for brushing

Instructions
 

Preparation

  • Preheat the oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish.
  • In a large bowl, combine cooked chicken, cream of chicken soup, sour cream, milk, and frozen vegetables. Add garlic powder, onion powder, salt, and pepper. Stir until smooth.
  • Fold in the quartered biscuit pieces until they are well coated in the mixture.

Assembly and Baking

  • Pour everything into the prepared baking dish. Sprinkle shredded cheese evenly over the top.
  • Cover the dish with foil and bake for 20 minutes.
  • Remove the foil and bake for an additional 10–15 minutes, until the biscuits are puffed, golden, and fully cooked.
  • Brush with melted butter if desired. Let cool slightly before serving.

Notes

Serve warm with a simple side salad or steamed vegetables. Leftovers can be stored in the refrigerator for up to 3-4 days or frozen in a freezer-safe container.
Keyword biscuits, Casserole, Chicken, Comfort Food, Easy Dinner